LEXINGTON, Ky. -- Tyler Ulis scored 20 points, Derek Willis added a career-best 18 and No. 20 Kentucky used an early 20-0 run to blow past outmanned Missouri 88-54 on Wednesday night.

The Wildcats (16-4, 6-2 Southeastern Conference) had it easy in improving to 9-0 against the Tigers and winning their third straight overall. Kentucky spotted the Tigers an opening layup by Wes Clark before the big spurt that quickly put the game out of reach, twice stretching its lead to 40 points in the second half.

Willis also grabbed 12 rebounds for his second double-double in four games. Isaiah Briscoe had 15 points, Skal Labissiere 12 and Jamal Murray 11 to round out Kentucky's double-figure scorers.

Clark had 11 points for Missouri (8-12, 1-6 SEC), which sustained its biggest loss this season.