Manny Ramirez downplayed his 400th career home run. He also probably underestimated the value of the milestone baseball.

"I'm going to put it on eBay and see how much I get," Ramirez jokingly said. "Maybe $200?"

Ramirez became the 39th player in major league history to reach 400 homers when he hit a three-run shot off Gil Meche in the fifth inning of the Boston Red Sox's 5-4 loss to the Seattle Mariners on Sunday.

He's just the fifth player to accomplish the feat as a member of the Red Sox, joining Jimmie Foxx, Ted Williams, Carl Yastrzemski and Andre Dawson.

Ramirez hit a 1-1 fastball from Meche an estimated 404 feet into the seats in right-center field. It was his 10th homer of the season and second in the three-game series against Seattle.

"I knew it would happen someday," Ramirez said. "I wasn't trying to put pressure on myself. I'm just happy to accomplish it."

Ramirez is the 13th player to reach the mark before his 33rd birthday, and just the fourth since Harmon Killebrew in 1969. He's also the fifth-fastest to get to 400, doing it in his 5,695th at-bat. Only Mark McGwire (4,726), Babe Ruth (4,854), Killebrew (5,300) and Jim Thome (5,416) got there faster.

"I hope he hits another 400 ... like in the next three years," Boston manager Terry Francona said. "I think he's excited. I do really think it meant something to him."

Cubs' Zambrano sore

Chicago Cubs right-hander Carlos Zambrano had an MRI on his sore elbow Monday, and the team is unsure if he will make his next start.

Zambrano, who is scheduled to start Friday against the White Sox, will throw on the side Wednesday in Pittsburgh.