Medical pot only OK for sick kids failed by other drugs, MDs say

CHICAGO -- With virtually no hard proof that medical marijuana benefits sick children, and evidence that it may harm developing brains, the drug should only be used for severely ill children who have no other treatment option, the nation's most influential pediatricians group says in a new policy.

Some parents insist that medical marijuana has cured their children's troublesome seizures or led to other improvements, but the American Academy of Pediatrics' new policy says rigorous research is needed to verify those claims.

To make it easier to study and develop marijuana-based treatments, the group recommends removing marijuana from the government's most restrictive drug category, which includes heroin, LSD and other narcotics with no accepted medical use, and switching it to the category which includes methadone and oxycodone.

The recommended switch "could help make a big difference in promoting more research," said Dr. Seth Ammerman, the policy's lead author and a professor of pediatrics and adolescent medicine at Stanford University.

The academy's qualified support may lead more pediatricians to prescribe medical marijuana, but the group says pediatric use should only be considered "for children with life-limiting or severely debilitating conditions and for whom current therapies are inadequate."

The academy also repeated its previous advice against legalizing marijuana for recreational use by adults, suggesting that may enable easier access for children. It does not address medical marijuana use in adults.

Studies have linked recreational marijuana use in children with ill effects on health and brain development, including problems with memory, concentration, attention, judgment and reaction time, the group's policy emphasizes.

The policy was published online Monday in Pediatrics. It updates and expands the group's 2004 policy.

Since then, the marijuana movement has grown substantially. Recreational and medical marijuana use is legal for adults in four states -- Alaska, Colorado, Oregon and Washington. Nineteen other states and Washington, D.C., have laws allowing medical marijuana use only and most allow children to qualify, according to Morgan Fox of the Marijuana Policy Project, a national group that advocates marijuana policy reform and tracks state laws.

"The cart is so far ahead of the horse related to this drug," said Dr. Angus Wilfong, of Texas Children's Hospital in Houston. Marijuana has dozens of chemical components that need to be studied just like any drug to determine safety, proper doses and potential side effects, he said.

Wilfong was involved in a recently completed international study involving 30 children with severe epilepsy. About half got an experimental drug made with a marijuana compound that doesn't make users high; the others received dummy medicine. Study results are being analyzed. Wilfong said five children from his hospital were involved and while he doesn't know if any of them got the marijuana drug, none suffered any serious side effects.

Wilfong said he has a young seizure patient in a different, less rigorous study who has shown dramatic improvement after several months on the marijuana-based treatment, "but that doesn't prove it was due to the" experimental drug," he said.

Online: American Academy of Pediatrics: http://www.aap.org

Medical marijuana: http://tinyurl.com/axxzhrj

AP Medical Writer Lindsey Tanner can be reached at http://www.twitter.com/LindseyTanner